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Biblioteca (s) : |
INIA La Estanzuela. |
Fecha : |
16/02/2017 |
Actualizado : |
24/06/2021 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Autor : |
PHAN, T.G; GIANNITTI, F.; ROSSOW,S.; MARTHALER,D.; KNUTSON, T.; LI, L.; DENG, X.; RESENDE, T.; VANNUCCI, F.; DELWART, E. |
Afiliación : |
FEDERICO GIANNITTI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
Título : |
Detection of a novel circovirus PCV3 in pigs with cardiac and multi-systemic inflammation. |
Fecha de publicación : |
2016 |
Fuente / Imprenta : |
Virology Journal, 2016 v.13 n. 1. p. 184 |
DOI : |
10.1186/s12985-016-0642-z |
Idioma : |
Inglés |
Notas : |
OPEN ACCESS |
Contenido : |
Abstract.
Background: Porcine circovirus 2 causes different clinical syndromes resulting in a significant economic loss in the
pork industry. Three pigs with unexplained cardiac and multi-organ inflammation that tested negative for PCV2 and
other known porcine pathogens were further analyzed.
Methods: Histology was used to identify microscopic lesions in multiple tissues. Metagenomics was used to detect
viral sequences in tissue homogenates. In situ hybridization was used to detect viral RNA expression in cardiac tissue.
Results: In all three cases we characterized the genome of a new circovirus we called PCV3 with a replicase and capsid
proteins showing 55 and 35 % identities to the genetically-closest proteins from a bat-feces associated circovirus and
were even more distant to those of porcine circovirus 1 and 2. Common microscopic lesions included non-suppurative
myocarditis and/or cardiac arteriolitis. Viral mRNA was detected intralesionally in cardiac cells. Deep sequencing in
tissues also revealed the presence of porcine astrovirus 4 in all three animals as well as rotavirus A, porcine cytomegalovirus
and porcine hemagglutinating encephalomyelitis virus in individual cases.
Conclusion: The pathogenicity and molecular epidemiology of this new circovirus, alone or in the context of
co-infections, warrants further investigations. |
Palabras claves : |
ARTERIOLITIS; ARTEROLITIS; CIRCOVIRUS; METAGENÓMICA; METAGENOMICS; MIOCARDITIS; PIG; VASCULITIS. |
Thesagro : |
CERDO. |
Asunto categoría : |
L73 Enfermedades de los animales |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/6477/1/Virology-Journal-2016-13.p.184-Phan-et-al..pdf
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Marc : |
LEADER 02290naa a2200361 a 4500 001 1056664 005 2021-06-24 008 2016 bl uuuu u00u1 u #d 024 7 $a10.1186/s12985-016-0642-z$2DOI 100 1 $aPHAN, T.G 245 $aDetection of a novel circovirus PCV3 in pigs with cardiac and multi-systemic inflammation.$h[electronic resource] 260 $c2016 500 $aOPEN ACCESS 520 $aAbstract. Background: Porcine circovirus 2 causes different clinical syndromes resulting in a significant economic loss in the pork industry. Three pigs with unexplained cardiac and multi-organ inflammation that tested negative for PCV2 and other known porcine pathogens were further analyzed. Methods: Histology was used to identify microscopic lesions in multiple tissues. Metagenomics was used to detect viral sequences in tissue homogenates. In situ hybridization was used to detect viral RNA expression in cardiac tissue. Results: In all three cases we characterized the genome of a new circovirus we called PCV3 with a replicase and capsid proteins showing 55 and 35 % identities to the genetically-closest proteins from a bat-feces associated circovirus and were even more distant to those of porcine circovirus 1 and 2. Common microscopic lesions included non-suppurative myocarditis and/or cardiac arteriolitis. Viral mRNA was detected intralesionally in cardiac cells. Deep sequencing in tissues also revealed the presence of porcine astrovirus 4 in all three animals as well as rotavirus A, porcine cytomegalovirus and porcine hemagglutinating encephalomyelitis virus in individual cases. Conclusion: The pathogenicity and molecular epidemiology of this new circovirus, alone or in the context of co-infections, warrants further investigations. 650 $aCERDO 653 $aARTERIOLITIS 653 $aARTEROLITIS 653 $aCIRCOVIRUS 653 $aMETAGENÓMICA 653 $aMETAGENOMICS 653 $aMIOCARDITIS 653 $aPIG 653 $aVASCULITIS 700 1 $aGIANNITTI, F. 700 1 $aROSSOW,S. 700 1 $aMARTHALER,D. 700 1 $aKNUTSON, T. 700 1 $aLI, L. 700 1 $aDENG, X. 700 1 $aRESENDE, T. 700 1 $aVANNUCCI, F. 700 1 $aDELWART, E. 773 $tVirology Journal, 2016$gv.13 n. 1. p. 184
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Registro original : |
INIA La Estanzuela (LE) |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas; INIA Tacuarembó. |
Fecha actual : |
21/02/2014 |
Actualizado : |
17/12/2019 |
Tipo de producción científica : |
Serie Técnica |
Autor : |
GIMENEZ, A.; BAETHGEN, W. (Ed.). |
Afiliación : |
AGUSTIN EDUARDO GIMENEZ FUREST, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; WALTER E. BAETHGEN, Universidad de Columbia/ IRI (International Research Institute for Climate and Society),. |
Título : |
SIMERPA: Sistema de información y monitoreo para la evaluación de riesgos climáticos en la producción agrícola de Uruguay y Paraguay |
Fecha de publicación : |
2007 |
Fuente / Imprenta : |
Montevideo (Uruguay): INIA, 2007. |
Páginas : |
50 p. |
Serie : |
(INIA Serie Técnica ; 162) |
ISBN : |
978-9974-38-231-2 |
ISSN : |
1688-9266 |
Idioma : |
Español |
Notas : |
Incluye CD-ROM |
Thesagro : |
ACCIDENTES ATMOSFERICOS; AGRICULTURA; CLIMATOLOGIA; DESASTRES NATURALES; GESTION DE RIESGOS; PARAGUAY; PRODUCCION; SISTEMAS DE ALERTA RAPIDA; SISTEMAS DE INFORMACION; URUGUAY. |
Asunto categoría : |
P40 Meteorología y climatología |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/6557/1/18429230309163133.pdf
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Marc : |
LEADER 00865nam a2200289 a 4500 001 1003313 005 2019-12-17 008 2007 bl uuuu u00u1 u #d 020 $a978-9974-38-231-2 022 $a1688-9266 100 1 $aGIMENEZ, A. 245 $aSIMERPA$bSistema de información y monitoreo para la evaluación de riesgos climáticos en la producción agrícola de Uruguay y Paraguay 260 $aMontevideo (Uruguay): INIA$c2007 300 $a50 p. 490 $a(INIA Serie Técnica ; 162) 500 $aIncluye CD-ROM 650 $aACCIDENTES ATMOSFERICOS 650 $aAGRICULTURA 650 $aCLIMATOLOGIA 650 $aDESASTRES NATURALES 650 $aGESTION DE RIESGOS 650 $aPARAGUAY 650 $aPRODUCCION 650 $aSISTEMAS DE ALERTA RAPIDA 650 $aSISTEMAS DE INFORMACION 650 $aURUGUAY 700 1 $aBAETHGEN, W.
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